Arix Bioscience takes stake in Aussie fibrosis specialist Pharmaxis
Arix led a A$24mln (£13.4mln) primary placing and will invest A$14.2mln itself in two tranches
Company
ASX:PXS
Syntara Ltd is a clinical-stage drug development company focused on the development of novel therapeutics aimed at correcting extracellular matrix (ECM) dysfunction. This will lead to positive outcomes in a range of diseases with high unmet need, including haematological malignancies such as myelofibrosis and myelodysplastic syndrome, chronic fibrosis (including skin scarring, pulmonary fibrosis, chronic kidney disease, NASH and cardiac fibrosis) and neuroinflammation.
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Arix led a A$24mln (£13.4mln) primary placing and will invest A$14.2mln itself in two tranches
Investments and investor services
At the close, the UK blue chip index was 4.68 points higher at 7,663.78, just below the session peak of 7,681.86, having recovered from a low of 7,636.60
Investments and investor services
The capital raising was priced at a premium to the last traded share price.
The company plans to raise funds by way of a share placement.
The company finished the June quarter with just over $31 million in cash.
Final stages of phase I studies and phase II enabling toxicity studies are due to complete in Q3 2018.
Large pharma companies are being attracted to the company’s drug development portfolio.
Value inflection points are expected in a number of programs.
The payment has unlocked the full deal potential of $625 million.
Pharmaxis is a global leader in drug development for fibrosis and inflammation.
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A glance at some of the day's highlights from the Proactive Investors newswire
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Cancer Research UK was immensely impressed with the company and its technology
Synairgen will retain a 17% interest in any partnership across all fibrotic indications
The program scope has been doubled to encompass two lead candidates.
The company has made three new hires including a head of chemistry.
A Phase I clinical trial is to start later this year for the LOXL-2 inhibitor
The Pharmaxis drug discovery group has developed a number of selective small molecule inhibitors.
The Pharmaxis register contains international specialist biotech investors.
Boehringer Ingelheim initiates Phase IIa study of compound acquired from Pharmaxis.
Bronchitol® is an inhaled dry powder for the treatment of cystic fibrosis.
The company finished the June quarter with $21.5 million in cash and is expecting more milestone payments this year.
Pharmaxis has partnered its work on Bronchitol for the U.S. with Chiesi Group.
Pharmaxis held a $25.5 million cash balance at the end of March.
Pharmaxis is an Australian pharmaceutical research company.
Payments of circa A$42 million are expected this year.
The agreement is for the commercialisation of Bronchitol®.
The June quarter will keep investors leveraged to valuable news flow.
Today and yesterday, two substantial holders have increased their stakes.
Pharmaxis' partner has funded US$22 million of the expected US$26 million trial cost.
Buckingham has more than 25 years’ experience in the global pharmaceutical industry.
Pharmaxis is becoming a more enticing target for drug acquisition and partnerships.
The commencement of the trial will trigger a milestone payment.
Pharmaxis (ASX:PXS) chairman, Malcolm McComas has acquired 200,000 shares on market for a total cost of $54,167.
Mergers and acquisitions are increasing in the fibrosis and NASH space.
Gary Phillips, CEO, commented: "This research will bring together the acknowledged expertise of the Woolcock Institute and Pharmaxis in the field of cystic fibrosis."
Entry into the Russian market for Bronchitol is a significant achievement for the company as it looks to expand the drug’s customer base and increase its potential to generate revenue.
Market activity in the past has already confirmed that the treatment of NASH is one of the hottest areas in biotech and Allergan’s takeover bid for Tobira has only added fuel to the fire.
Progress under the new business model over the 2016 financial year has been substantial. The company finished the financial year with a cash balance of $39 million and net cash usage over the year of $15 million.
Gary Phillips, CEO, commented: "We are pleased to have attained this significant milestone in such a large undertaking securing more than 400 study participants at 126 sites in 21 countries."
BIO is the largest global event for the biotech industry with nearly 16,000 industry leaders from 76 countries attending the conference and over 3,400 companies participating in partnering meetings.
Strengthening relationships, a multi-pronged research program and an agenda for milestone payments have Pharmaxis in good shape.
The Australian All Ordinaries rebounded today with strong performances from all sections except mining, where price woes continue to cause concern. This medical play added to the momentum for health stocks with another positive showing.
The Australian All Ordinaries rebounded 2.3% today to 5,079 points with help from a strongly advancing pharmaceutical researcher.
Pharmaxis has received positive trial results for its cystic fibrosis treatment, Bronchitol, setting the company up to expand its marketing of the drug in Europe as a plan to penetrate the U.S. market develops.
Pharmaxis Limited more than doubled its cash at bank year-on-year to A$50.3 million at the end of the September quarter as the company realised significant drug trialling and collaborative research milestones.
The successful clinical trial will enable one of the world’s 20 leading pharmaceutical companies, Boehringer Ingelheim, to proceed with further development of the program. Boehringer Ingelheim, a leader in cardiometabolic and respirat
The collaboration with Synairgen could accelerate development of the lung disease treatment while reducing risks on the path to value points. Pharmaxis has executed three deals in six months and is tapping into a rich seam of potential drug