AstraZeneca receives EU approval for lung cancer drug Tagrisso
Tagrisso reduced the risk of disease recurrence or death by 80% in the overall trial population of patients
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LON:AZN
AstraZeneca is one of the world's leading pharmaceutical companies, with a broad range of medicines designed to fight disease. AstraZeneca has over 67,000 empolyees and operates in over 100 countries with growing presence in important emerging markets.
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Tagrisso reduced the risk of disease recurrence or death by 80% in the overall trial population of patients
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Après Soriot, le déluge? Institutional investors have been cutting up rough more than usual this year over executive pay, although they have yet to win a significant victory.
The DNA-based formulations that have been linked to very rare cases of blood clots, some of which caused death
The notes must be redeemed before the maturity date if the deal doesn’t happen before March 2022 or if it gets scrapped
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Two doses are required to get strong protection against the new strain
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The Vaxzevria jab will be administered in two doses given four to 12 weeks apart
Government has said that it is confident the vaccines are effective against the Indian variant.
AstraZeneca, Rio Tinto and Glencore are part of a long list of companies that are facing backlash over remuneration packages
The pay proposal includes bonuses of £12mln or more
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The candidate was analysed in combination with platinum-based chemotherapy, or antibody tremelimumab and chemotherapy, compared to chemotherapy alone
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UK – Strong manufacturing PMI data released this morning with growth in production and new orders among the strongest in the past seven years leading to a solid increase in employment. Further loosening of COVID-19 restrictions at home and
The pharma giant is “becoming a cleaner story for investors to own”, analysts said
The firm said it is the most significant advancement in the treatment of chronic kidney disease in more than 20 years
AstraZeneca was in court defending itself this week after the EU launched legal action
The pharma giant said the second half will see a boost in performance
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Footsie finished Friday ahead by around eight points, or 0.12%, at 6,969,
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FTSE 100 giants AstraZeneca and Barclays are set to declare first-quarter results on Friday
The EU Commission has sued the pharma giant over COVID-19 vaccine deliveries
The offer will consist of 6.5mln American Depositary Shares (ADS) priced at US$16-18 each
All 27 states backed the legal challenge, which started last Friday
A Dutch official said the doses will be left behind once the country receives supplies from other manufacturers
An EMA committee recommended conditional marketing authorisation for both selumetinib and tagrisso
The first dose of a COVID-19 vaccine was enough to push infections down by 65%
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The pharma giant should tread carefully, analysts said, as the EU is a vital part of its business
The pharma firm agreed to acquire the rare disease specialist in December last year in a deal worth US$39bn
Cases were more common after COVID-19 than in any of the comparison groups, with 30% of these cases occurring in the under 30s
Mixing vaccines could allow for a more flexible rollout and to make up for shortfalls of doses, researchers said
The bloc is planning to focus on mRNA-based vaccines, such as those produced by Pfizer and Moderna
More than a third of the world's lung cancer patients are in China
The primary goals were prevention of organ dysfunction and death as well as recovery over 30 days
Also, a new study suggests there is a correlation between the fall in deaths and the vaccine rollout in the UK
Both UBS and Citi restated their guidance on the stock
One of the co-founders is Sarah Gilbert, the University of Oxford professor behind the vaccine
The authorities stressed that the jab's benefits continue to outweigh the risks
The benefits in preventing the disease outweigh risks of side effects, the EMA said
The shot is expected to be used in the rest of the United Kingdom by the middle of April.
Valneva's vaccine VLA2001 also sparked broad T-cell responses
“No decision has yet been made on any regulatory action.”
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The UK blue chip index remained buoyant but Wall Street sees some profit taking after this week's new records
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Business minister Kwasi Kwarteng said the “focus has to be to try and keep Britain safe” as over 30mln people have received a jab
Meanwhile, the University of Oxford is launching a study to deliver the vaccine via a nasal spray instead of injecting it
The primary analysis will be the basis for a regulatory submission for Emergency Use Authorization in the US
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It is understood that AstraZeneca may have included outdated information from that trial, which may have provided an incomplete view of the efficacy data
The Commission is looking to prevent jabs made on the continent to be delivered abroad because AstraZeneca is not meeting contractual obligations
An independent committee found no increased risk of thrombosis in late-stage trials of over 32,000 people
Experts from the European Medicines Agency are discussing whether to keep rolling out the jab in the bloc
The US investment bank reckons the risk-reward is significantly more positive
The European Medicines Agency will issue a decision on Thursday
The total value of the contracts with US governments concerning the AZD7442 candidate is US$726mln
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The European Medicines Agency has said it has not found any evidence of causality; correlation is not causation, as the old adage has it.
Several EU countries and Thailand have put the jab rollout on hold over concerns of blood clots reports in Norway
On Monday, Austria suspended vaccinations after a 49-year old nurse died from severe blood clots.
The pharma giant has been in litigation against Mylan and Kindeva
Shares in Moderna have rocketed over 400% since a year ago after it successfully developed a COVID-19 jab
The withdrawal is in line with guidance on accelerated approvals that did not meet post-marketing requirements
The firm is testing modified versions of the current vaccine with clinical trials earmarked for the spring
Sales have been rising thanks to new medicines, with plans to further invest in research and development
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Britain's blue-chip benchmark finished the day up around four points at 6,528
AstraZeneca and Royal Mail are among the notable names in Thursday's diary.
The AstraZeneca vaccine and the alternative developed by Pfizer/BioNTech both work very well against the original form of Covid-19.
Earlier this week, Curevac announced it had agreed a €150mln joint venture with GlaxoSmithKline to develop mRNA-based vaccines
Insights from the KESTREL Phase III trial will advance our understanding and application of immunotherapy, the FTSE 100 company said
Participants will receive different COVID-19 vaccines for their first or second dose
The therapy can be used in adults with heart failure with problems to the left ventricle and without type-2 diabetes
The jab was safe and offered complete protection against hospitalisation and death
This weel AstraZeneca is expected to release tests on its vaccine against the new strain, with most competitors reporting lower efficacy rates
The row between the pharma giant and the bloc has culminated in a promise for more supplies, while the UK is on track to meet its mid-February vaccination target
The approval will come hours after the EU published the contract signed with the pharma giant to back up its requests
Meanwhile, French firm Valneva has begun large-scale vaccine manufacturing in Scotland
UK deaths attributed to virus rose to more than 100,000 yesterday
AstraZeneca can only deliver half of the doses promised for the first quarter but officials said the explanations were insufficient
Symbicort Turbuhaler was already approved in the Asian country for patients with moderate to severe symptoms
The same candidate, Calquence, also met its main goal in another trial on blood cancer patients
The co-founders of BioNTech were involved in the study
Over half a million women in Europe are diagnosed with the disease annually
The latest news on the UK's COVID-19 vaccination programme
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In today's coronavirus news, updates on the vaccine programme in the UK and results from a study on former patients
There were various major developments regarding COVID-19 vaccines on Thursday
Meanwhile, Scotland is entering lockdown on Monday at midnight
The FTSE 100 firm has provided 530,000 doses ready for use on Monday at six hospital trusts
The buyer is German pharma company Cheplapharm, which paid US$250mln on completion of the deal and will pay the balance in the first half of 2021
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The FTSE 100 index closed out the last session of this benighted year 95.30 points lower at 6,460.52, a level last seen in July 2016
Hancock said that recent surge in infections had made tougher restrictions necessary across the country.
People aged 18 or over will receive two shots of the vaccine with the second dose administered 4-12 weeks after the first.
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The UK blue-chip index closed down 46.83 points, or 0.7% at 6,555.82, only just above the session low of 6,552.466, and well below the early peak of 6,622.98
A new study has indicated that 2mln people a week in the UK would need to be vaccinated to avoid a third wave of the coronavirus outbreak
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At the close, the UK blue-chip index was up 100.54 points, or 1.6% at 6,602.65, albeit well below the session peak of 6,676.60
“I would expect some news pretty shortly, I doubt we will make Christmas now but just after Christmas I would expect.”
Tagrisso will be used to target the early-stage epidermal growth factor receptor-mutated form of the disease
The deal comes six and a half years after the advances of Pfizer were rejected, nixing what would have been the biggest ever takeover of a UK company by a foreign rival
The acquisition is expected to close in the third quarter of 2021 and produce around US$500mln of savings in three years as well as strengthening cash-flow generation
Russian scientists have claimed that as the two are both common-cold based treatments combining them would greatly enhance the Astra vaccine,
Chris Whitty says vaccine will greatly reduce hospital admissions