Tiziana Life Sciences Ltd announced that the US Food and Drugs Administration (FDA) has accepted its request to enroll a second patient onto the ongoing clinical treatment of secondary progressive multiple sclerosis (SPMS).
Tiziana, a biotechnology company that enables immunotherapies via novel routes of drug delivery, is evaluating nasally administered foralumab for SPMS.
NetScientific PLC (AIM:NSCI) flagged new that portfolio company, PDS Biotechnology, has been granted a US patent for its PDS0101 immunotherapy.
The application was based on a paper entitled, "Novel HPV16 Non HLA-Restricted T-cell Vaccines, Composition and Methods of Use Thereof".
FinnCap has doubled its price target for Chariot Ltd (AIM:CHAR, OTC:OIGLF) as it confirmed the Anchois field as a significant discovery, with an appraisal well encountering multiple pay zones.
Jonathan Wright, analyst at FinnCap, in a note, called it excellent news which has seen the company’s transformational gas strategy “come good at the first time of asking”.
Genflow Biosciences PLC will become the first longevity-focused biotech ever to float in Europe when joins the London Stock Exchange’s standard list.
An oversubscribed placing of shares has raised £3.7mln and ascribed an initial valuation of £23.4mln to the fledgling business.
Bradda Head Lithium Ltd (AIM:BHL) said it exercised its option to acquire 100% of the Burro Creek project area and a portion of Burrow Creek West.
It takes the total land area of sedimentary lithium claims held by Bradda Head in Arizona to 47 square kilometres.
Chariot Ltd (AIM:CHAR, OTC:OIGLF) confirmed a 'significant' gas discovery at the Anchois-2 well offshore Morocco which materially exceeded expectations.
Anchois-2 well was drilled to a total depth of 2,512 metres and encountered significant gas accumulations with the appraisal target, Sand B, marking some 50 metres of net pay across two stacked reservoirs – the uppermost was the reservoir seen in the original discovery well.
Scientists at the National and Kapodistrian University of Athens used ANGLE PLC (AIM:AGL, OTCQX:ANPCY)’s liquid biopsy system to assess why non-small lung cancer patients become resistant to treatment.
The Parsortix liquid biopsy was used to harvest circulating tumour cells for DNA analysis to find the molecular mechanisms that lead to the progression of the disease. The team assessed the ongoing efficacy of AstraZeneca's Tagrisso.
NetScientific PLC (AIM:NSCI) said its investee company ProAxsis made significant progress last year.
Among the highlights for the diagnostics business was the development of NE Premium assay with 100-fold improved sensitivity to the current product.
Supermarket Income REIT PLC has declared an interim dividend of 1.485p per share for the fourth quarter of 2021. The real estate investment trust said the payment will be on or around 25 February, with the ex-dividend date of 20 January. It will be paid as a property income distribution in respect of the Company's tax-exempt property rental business.
Bacanora Lithium PLC provided an update to its announcement on 22 June 2021 regarding its debt facility with RK Mine Finance, saying it has now fully repaid all amounts due under the June 2018 first tranche drawdown of US$25mln, as well as settled the 6mln warrants issued at the time. Accordingly, it said all securities registered under this facility will now be removed.
Powerhouse Energy Group PLC noted that Hydrogen Utopia International PLC (HUI), a licensee of Powerhouse technology, has had its ordinary shares admitted to trading on the AQSE Growth Market last week. HUI raised £3mln to help it achieve its aims of becoming one of the leading new European companies specialising in turning non-recyclable mixed waste plastic into carbon-free fuels such as syngas, hydrogen and electricity, new materials or distributed renewable heat.
Mila Resources PLC has been notified that on 7 January 2022, executive director Mark Stephenson bought 1mln ordinary shares in the company at a price of 2.4p each. Following this transaction, his total beneficial interest in the company is 6,116,761 shares, representing 2% of the total issued share capital.
Oracle Power PLC announced that directors of the company have purchased ordinary shares in the company as part of the MAR compliant director share purchase plan.