Pharmaxis Ltd

Pharmaxis gains new substantial holder with 6.89% interest

The company is developing a pipeline of products to treat inflammation and fibrosis.

Pharmaxis' top 20 shareholders held 68.6% of the company end of 2018

Pharmaxis Ltd (ASX:PXS) has gained a substantial holder in D&A Income Limited which now holds more than 27 million Pharmaxis shares representing a 6.89% interest.

D&A initially held abut 8 million shares but purchased a further 19.1 million late last month for a cash consideration of more than $5 million.


Pharmaxis is an Australian pharmaceutical research company focused on inflammation and fibrosis with a portfolio of products at various stages of development and approval.

The company’s development pipeline focuses on its expertise in amine oxidase chemistry and includes:

  • A series of lysyl oxidase like 2 (LOXL2) inhibitors targeting fibrotic diseases of the liver, heart, kidney and lunch that recently completed phase-one clinical trials;

  • A lysyl oxidase (LOX) inhibitor in development for pancreatic cancer that recently completed preclinical development; and

  • A potent inhibitor of semicarbazide-sensitive amine oxidase (SSAO) called BI 1467335 to develop treatment for the liver-related condition non-alcoholic steatohepatitis (NASH) and other inflammatory diseases.

Pharmaxis manufactures and exports its approved products from its facility in Sydney, including Bronchitol for the treatment of cystic fibrosis and Aridol, a lung function test for asthma.

Quick facts: Pharmaxis Ltd

Price: $0.19

Market: ASX
Market Cap: $72.99 m

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Pharmaxis hopeful of FDA approval for cystic fibrosis inhalation medicine...

Pharmaxis Ltd (ASX:PXS) chief executive officer Gary Phillips updates Proactive Investors on the FDA approval timeframe for the company’s Bronchitol inhalation medicine used to treat adult cystic fibrosis patients. The healthcare-focused company is confident it will meet information...

on 13/8/19

2 min read