The Body Shop is closing half of its stores in the UK after the struggling retailer fell into administration last week.
Seven sites will close today including sites in Oxford Street, Canary Wharf, Bristol and Ashford.
Around 40% of workers at its London-based head office are also expected to be axed.
Under half of the remaining 198 outlets are expected to also close, putting more than 2,000 jobs at risk,
Administrators said the decision comes as it is "no longer viable" to keep its estate after "years of unprofitability".
The FTSE 100 slipped 16 points lower at around 7,710.