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FTSE 100 closes in red, despite US market turnaround
In London, the FTSE 100 closed down around 29 points at 7,252
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LON:GSK
GSK PLC will be a fully focused biopharma company following the demerger of its world-leading consumer healthcare business, Haleon, in July 2022. The company will prioritise innovation in vaccines and specialty medicines, maximising the increasing opportunities to prevent and treat disease.
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Investments and investor services
In London, the FTSE 100 closed down around 29 points at 7,252
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Day ahead includes a swathe of FTSE 100 results, including from the likes of Barclays PLC, British American Tobacco PLC, BAE Systems PLC, and Centrica PLC
Shares in Reckitt have continued to decline after Monday's disappointing results as JP Morgan cut its 2018 earnings guidance and target price
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The minister responsible for Britain's exit from the EU, David Davis said the UK would lead a “global race to the top"
The group returned to like-for-like revenue growth in the fourth quarter..
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Week ahead includes a deluge of blue chip results, notably from the banking sector, including numbers from HSBC PLC, Barclays PLC, Lloyds Banking Group PLC, and Royal Bank of Scotland PLC
Is the market being too negative about the prospects for the HIV franchise and generic competition to its best-selling asthma treatment, Advair?
GSK’s one pill, once daily treatment was approved back in November, while Gilead’s drug got the green light from the US FDA on Wednesday
If a generic competitor comes to market this summer as expected, GSK said earnings will fall by between 0-3%, while if a competitor isn’t forthcoming, earnings will rise by 4-7%
The UK blue chip index closed up 138 at 7,279 - above the day’s peak of 7,255.
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Rio Tinto is expected to carry on returning piles of cash to shareholders but some people think a dividend cut at Glaxo is on the cards
The UK blue chip index closed down 108.45 points at 7.334, which had been the session low
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After November's hike, another UK rate rise is unlikely this month, although some Bank of England MPC members may vote for a rise after a unanimous vote in December
GSK is paying Neurometrix US$5mln up front plus up to US$21.5mln in milestone payments to acquire the exclusive ownership of the Quell technology
Analyst Emmanuel Papadakis has upgraded GSK to ‘overweight’ and hiked his price target to £16.50, claiming that any risks are now priced in, while progress has been made in HIV and shingles
In the dose expansion phase of its DREAMM-1 phase I/II study of GSK2857916, the antibody-drug conjugate demonstrated a 60% response rate and median progression-free survival of 7.9 months
People who have undergone stem cell transplants typically have weaker immune systems, which makes them more susceptible to viruses such as shingles
The trial will evaluate the effectiveness of an injectable HIV drug, administered only once every two months, in sexually active women
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Some of the biggest risers and fallers in London on Wednesday
Investments and investor services
London's blue-chip index closed the day lower but retailers and housebuilders did well, oh, and there was some Brexit news...
Uncertainty surrounding the trajectory of GSK’s ViiV Healthcare HIV business justifies a discount argues UBS analyst Michael Leutchen, but he reckons the valuation now reflects that
Juluca – as the treatment is known – is made by GSK’s majority-controlled ViiV Healthcare and is the first such drug to be approved by US authorities
The strong demand for Tivicay and Relvar, among others, justifies new boss Emma Walmsley’s decision to narrow the drugmaker’s focus on HIV and respiratory medicines
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The UK blue chip index closed down 1.05% to 7,447 as the pound strengthened after better-than-forecast UK GDP
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PPI, the HBOS acquisition and now the prospect of a rate rise hitting the mortgage market; it's all a bit of a trial for Lloyds
The UK healthcare cost regulator has approved GSK's gene therapy for so-called 'bubble boy' syndrome while the US FDA has approved its shingles vaccine
The week ahead includes third quarter earnings from Lloyds, Barclays and RBS along with trading updates from Shire, IAG and GSK
A look at some of the biggest risers and fallers today in London
The UK blue chip index closed at 7,526, well below the session peak of 7,557.00 and close to the day’s low of 7,531.48
The once-a-day triple inhaler combines the drugs fluticasone furoate, umeclidinium and vilanterol and will have a proposed brand name of Trelegy Ellipta
Shire remains the "standout stock" as it has an "extremely compelling valuation”, according to JP Morgan
A study of GSK's Relvar Eillipta treatment showed an improvement in symptoms of asthma sufferers
The FTSE 100 retreated as investors worry about Hurricane Irma, while mixed economic statistics raised fresh concerns over the UK economy.
Mike van Dulken, head of research at Accendo Markets said the share price reaction “may in fact be due to a downgraded Risk & Uncertainties statement, buried half way through the report before the financial statements"
The FTSE 100 finished 108 points lower at 7,390, about 13 points above its intra-day low
Sources are cited as saying the bidding could go as high as US$200 a share, valuing the business at US$8.7bn
More than 30 pre-clinical and clinical programmes will be stopped, divested or partnered out, it emerged
Not entirely unexpected was the trimming of full-year earnings guidance. That said, it precipitated a modest sell-off with the stock down 1.6% in afternoon trade, wiping £1bn from the value of GSK.
The blue chip index has more than made up for the miserable start to the week with a solid showing both yesterday and today...
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The recently-announced sale of Horlicks may be the sign of an increased focus on the drugs pipeline
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Week ahead: Lloyds, Barclays, AstraZeneca, GlaxoSmithKline, Sky, Reckitt Benckiser
London stocks were on the front foot this morning, but they quickly retreated this afternoon...
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Next week is a big one for Emma Walmsley, GlaxoSmithKline’s newish chief executive.
GSK's new chief executive wants the company to focus on its pharmaceuticals business as it comes under increased pressure from generic drug competitors
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The blue chip index closed up 40.69 at 7,430 on the day
ITV, Burberry and GlaxoSmithKline could face potential bids from international rivals as a weaker pound stokes interest in a number of UK-based firms
Citi has gone to ‘neutral’ from ‘buy’ on GSK shares, which it reckons are worth £17 each
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The FTSE 100 index was closed up 10.37 at 7,367 on Wednesday
Wall Street shares closed mixed , but the Dow Jones added 129 in the truncated session.
Exscientia will use its artificial intelligence enhanced platform to identify pre-clinical drug candidates for up to 10 disease-related targets
The Republicans are looking to repeal Obamacare as well as trying to ease regulatory pressures in the industry
The broker has been bullish on the sector since November’s US elections, in which time the sector has advanced 20%, or 12% in relative terms.
Despite the worst case scenario in the General Election, the FTSE 100 rose strongly
The submission is for a combination of dolutegravir, developed by ViiV Healthcare and Tivicay, and rilpivirine, developed by Edurant, and Janssen Sciences Ireland UC
Berenberg’s share price target moves to £18.85 from £18.50, prompting a recommendation upgrade to ‘buy’ from ‘hold’.
Hikma Pharmaceuticals has confirmed that it does not expect to launch its generic version of Advair this year
Concerns over "the Donald" appear to be easing, and investors took the opportunity to return to equity markets
The catalyst for the change is the likely delay to the introduction of a low-cost, copycat version of GlaxoSmithKline’s (LON:GSK) inhaled asthma drug, Advair, being developed by the company.
A look at some of the biggest London-listed risers and fallers today
Woodford Investment Management said it sees Lloyds as a "well managed bank" with the ability to pay a "very healthy and growing" level of dividend
At the close, the UK blue chip index was up 0.7%, or 48.8 points at 7,435.4, not far below its all-time record of 7,447.0
A look at some of the biggest London-listed risers and fallers today
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The Footsie was back in black - but only just - thanks to precious metals miners
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HSBC is the last of the big four banks to report with more uncertainty over the outcome than for its UK-centric rivals.
The FTSE 100-listed firm said its adjusted earnings per share rose by 31% to 25.0p in the quarter to March 31, beating forecasts for 24.5p
The FTSE 100 closed at 7,288 as traders look ahead to Donald Trump's tax plans
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Day ahead: BHP Billiton, GlaxoSmithKline, Proactis...
The FTSE 100 closed 150 points, or 2.11% higher, as investors welcomed Macron's result in the first round of France's presidential election
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Week ahead: Huge for blue chip announcements with four high street banks, the UK’s two pharma giants, mining titans Anglo and BHP and restaurant to coffee chain Whitbread just a few of those updating.
Google's promise to crack down on adverts from appearing alongside extremist content has failed to reassure clients
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The jobless rate fell to 4.7%, down from 4.8% last month, marking its lowest level since the summer of 1975, with economists having expected no change
“Our clear preference is for specialty-focus and growth in the context of a strong-catalyst driven thematic or deep value,” Barclays said in a brief note to clients.
We’ve had the final results from Holy Trinity of the UK pharma industry ... which is the one to back?
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Shire’s results Thursday will update on how 2016 ended as it provides commentary and numbers on the fourth quarter, which will be consolidated to provide full-year numbers too.
GSK says the results of its phase three study of its HIV treatment may change our understanding of how the virus can be managed.
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Shire will complete the fourth-quarter results announcements from the FTSE 100-listed pharma giants following numbers from Astra and Glaxo
Investments and investor services
FTSE 100 shares closed higher on Thursday in tandem with a US equity rally after President Donald Trump announced “phenomenal” corporate tax reform Wall Street had been waiting for with bated breath
US stocks recovered from intraday losses to end higher on Wednesday after analysts focused on a fall in gasoline inventories rather than a spike in oil supplies
Core earnings per share was 102.4p, at the top end of guidance for the year, but current year guidance was heavily caveated
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Glaxo is the next pharmaceuticals giant to update the market and it will probably be a familiar story of increased competition from generic versions of its blockbuster drugs.
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BP could please on Thursday as its recent quarterly updates have proved a little disappointing. GlaxoSmithKline will unveil its numbers Wednesday.
FTSE 100 stocks fell further below 7200 on Monday after sterling gained strength against the US dollar in the aftermath of President Donald Trump's inauguration speech
That at least is the opinion of the respected pharma team at Jefferies, which raised its valuation of shares Europe’s largest drugs firm.
FTSE 100 shares did it again on Thursday – the 11th successive record high close – as turbulence in sterling finally gave in to a further steady decline and helped push stocks higher. All except retailers, that is
Mir has gone for giants in the oil, pharma and broadcasting sectors
Richard Hunter is keeping tabs on AstraZeneca, GSK and ITV as we head into 2017
Glaxo has developed the new two-drug cocktail through its majority-owned ViiV Healthcare joint venture, in which US firm Pfizer and Japan’s Shionogi also hold stakes.
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FTSE 100 shares closed back above 7,000 on Friday for the first time since late October
The conventional forecasting tool-box is broken says the Swiss broker
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A look at some of the big, trending topics on Wednesday
The general consensus is that the decline in AstraZeneca’s share price now represents a good buying opportunity
Most sufferers are afflicted with a rash, but in the severest cases the disease can cause blindness and intense pain.
The closed triple combination therapy comprises three medicines delivered once-daily in GSK's Ellipta dry powder inhaler.
Some of the main news-driven share price changes at 3.30pm.
Markets have reacted badly to Trump's electoral victory, but some sectors have benefited
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“From a legislative angle, we continue to prefer names with either limited part D exposure [US Medicare] or heavier contribution of non-pharma assets."
Deutsche analyst Richard Parkes said the market beating sales were mainly down to the group's strong sales of vaccines, notably for flu - Bexsero, Boostrix and Synflorix.