GlaxoSmithKline needs to review top management, activist investor Elliott Management says
The request comes amid debates around the competence of chief executive Emma Walmsley
Company
LON:GSK
GSK PLC will be a fully focused biopharma company following the demerger of its world-leading consumer healthcare business, Haleon, in July 2022. The company will prioritise innovation in vaccines and specialty medicines, maximising the increasing opportunities to prevent and treat disease.
743 stories · page 4 of 8
The request comes amid debates around the competence of chief executive Emma Walmsley
Chief executive Emma Walmsley presented her new strategy on Wednesday in what was seen as a 'make it or break it' event for her career
Deutsche Bank upgraded its stock recommendation after the capital markets day
The new strategy seemed to please investors, who are set to ask more questions on Wednesday afternoon's event
Proactive's live blog of GSK's media call with Emma Walmsley
Archive
The pharma giant will kick off its eagerly anticipated investor day at the mid-point of the week
The chief executive may be heading for an uncomfortable Capital Markets Day with activist investor Elliott leading the questioning
The implied negative pipeline value is unwarranted as there are “gold star assets” with potential to fill the £3bn sales hole left by the upcoming dolutegravir patent expiry
The announcement came ahead of the group's capital markets day next week
The group has also announced the start of late-stage trials for the COVID-19 vaccine developed with Sanofi
The plant-based jab has been tested in combination with GSK's pandemic adjuvant
Approval may come a year later after their competitors, but the pair reckon there is a need for their candidate
The pair are targeting approval by the end of the year
Chief executive Emma Walmsley expressed firm commitment to her plans after the spinoff on Wednesday, which may leave Elliott Management little leeway with its agenda
Restrictions have hindered several of its programmes, but some issues may not resolve with the end of the pandemic
The pharma giant will release more updates on the Consumer Healthcare spinoff and a new dividend policy in June
The investment firm focuses on providing consultancy services to universities and other research organisations to help them commercialise any intellectual property arising from their research
JP Morgan expect revenue to slide 11% to £7.7bn after the rollout of Shingrix was hindered by the pandemic
The trial showed an overall response rate of 42.3% and a duration of response of six months or more for 93.3% of participants
Liberum expects a spike in revenue after short-term headwinds this and next year
The activist fund manager has acquired what was described as a significant stake,
Novavax is expecting a decision from the regulator as soon as next month
The inappropriate conduct would have happened while Moncef Slaoui was still working at the pharma giant
Medicago's candidate, in combination with Glaxo's pandemic adjuvant, has been granted Fast Track designation by the FDA
The pharma giant is developing a monoclonal antibody with US biotech Vir
The pharma giant is expanding the study to focus on the candidate's effects on patients aged over 70
“We are confident that our vaccine candidate has strong potential and we are very encouraged by the latest preclinical data"
Previous backers include GlaxoSmithKline, which invested US$300mln in 2018 as part of an exclusive four-year collaboration deal
Analysts remain cautious on the forecast growth rebound in 2022 because of COVID-19 disruption
FTSE 100 index falls 10 pointsUS stocks start mixedUS private sector adds 174k jobs in January2.47pm: Mixed start for US stocksThe Wednesday session on Wall Street was off to a mixed start on Wednesday as investors digested the latest set o
The firm is missing out on huge revenue upside from COVID-19 vaccines as it's months behind its competitors
The pair will work on new jabs targeting new variants of the virus
Wednesday is scheduled to bring heavyweight updates from both sides of the Atlantic, while the macro diary is scheduled to see new PMI data from the UK and US service sectors
Cabenuva reduces the treatment dosing days from 365 days to 12 days per year
Meanwhile, another broker has Glaxo as its top pick in a pharma sector that looks poised for growth
ViiV’s Vocabria used in combination with Janssen Pharmaceutical’s rilpivirine injection and tablets
It is the first setback in a largely successful quest for a vaccine
The bank said while the pharma firm saw the separation as an “opportunity to reset its debt” there were also questions about what would happen to its dividend
The results came from the first study of long-acting injectable therapy for HIV prevention among women
The broker sees structural risks from mergers and acquisitions and dividend uncertainty before the consumer spin out in 2022
The pharma company noted the increasing scientific evidence shows that climate issues affect human health
Analysts said the pharma company is undervalued in its prospects for growth
Revenues overall fell by 8% to £8.65bn, while operating profits dropped 13% to £1.87bn.
The two companies have signed a Statement of Intent with Gavi, the legal administrator of the COVAX Facility
Archive
The pharmaceutical giant will likely be eyed for any news on vaccination rates to help drive earnings, while retailer Next will be watched as a possible bellwether for the health of the wider UK retail sector
A look at the week's major news regarding the pandemic
The final trial is planned to start in December if data from the current one can support it
BLENREP is the fifth major medicine approval for GSK and the second from its oncology portfolio
A Phase 1/ 2 study is expected to start in September, followed by a Phase 3 study by the end of 2020
A round-up of Friday's major news regarding the pandemic
Over US$1bn are needed to support the jab’s development such as the trials on humans
There was a sharp drop off in the second quarter as disruption from COVID-19 began to be felt
Britain is to buy 60mln doses of the inoculation, which has yet to enter the clinic
President Trump was reported to have offered to pay for exclusive access to CureVac's COVID-19 vaccine
Analysts at Liberum see peak sales of £3.8bn if the drug is approved
The pharma giant is identifying potential vaccines that could be suitable to use the agent
Injectable cabotegravir is 69% more effective than daily tablets of emtricitabine/tenofovir disoproxil fumarate, the current standard of care
The pharma giant acquired the stake in December 2018 as part of a transaction with Unilever
Until now, only 20% of women with ovarian cancer were eligible to be treated with a drug of the same kind
"Responding to the Covid-19 pandemic is at the heart of our purpose as a company," said chief executive Emma Walmsley
The candidate would enter clinical trials in the second half of 2020 and be available by the end of 2021
Vir's has two candidates that have proved highly potent in neutralising SARS-CoV-2 in live virus-cellular assays
Full-year results showed turnover up 10% to £33.8bn and adjusted earnings per share up 4% to 123.9p, following a disappointing fourth quarter
Britain's blue chips closed up over 42 points at 7,482. The midcap FTSE 250 added around 94 at 21,534
Aside from Glaxo, first-half results will be eyed from housebuilders Barratt Developments and Redrow, with Vodafone to issue an update
FTSE 100 closed Monday ahead by around 40 points, or 0.55% at 7,326. Mid-cap cousin FTSE 250 gained over 63 at 21,207
Three housebuilders are also due to report on their numbers in the coming week: Barratt Developments, Bellway and Redrow
The ‘buy’ recommendation was maintained while the target price was lifted to 1,950p from 1,900p
Glaxo's specialist HIV drugs division, in which Pfizer and Shionogi have stakes, has been developing the once-a-month injection as an alternative to daily treatments
An injectable drug that launches in the US this year also might generate revenues of almost £700mln by 2023.
The drugmaker now expects adjusted EPS for 2019 to be “around flat” year-on-year, an upgrade from a decline of between 3% and 5%
Archive
The UK's premier share index finished ahead by 24.52 points at 7,330, having been lower earlier
The company said it decided to sell these brands to focus on other segments within its fast-growing vaccines business
The UK Medicines and Healthcare products Regulatory Agency (MHRA) said that all unexpired stock was going to be removed from pharmacies
GSK bosses will use the results from this latest DREAMM-2 trial as the basis for the regulatory filings
Glaxo already knew that its once-monthly jab worked, and it has now shown in clinical trials that the same injection but taken every two months is just as effective
Archive
A glance at some of the day's highlights from the Proactive Investors newswire
Midatech said it is "very confident" Frédéric Duchesne will make an "important and positive impact" to the business
Investments and investor services
Investors are expecting a cut of 0.25% in the benchmark short-term rate
GSK was forced to cut its forecasts earlier this ear after a generic rival to Advair came to market, but an “improved operational performance” in the second quarter means things won’t be as bad as first feared
Jonathan Symonds will be the man tasked with overseeing the mega merger of GSK and Pfizer’s consumer healthcare businesses
Investments and investor services
FTSE 100 closed in the red on Wednesday as miners weighed after a sell-off in iron ore in China
Archive
The Conservative Party leadership contest was decided by a relatively convincing margin of 92,153 votes to 46,656, while Love Island commands consolidated viewing figures of more than 5mln
Investments and investor services
In New York, the Dow Jones Industrials Average hit 27,153 by midday, while the S&P gained 0.2% and the Nasdaq was up 0.6%.
Archive
The week ahead includes updates from ITV, Unilever, Rightmove, Diageo, Marston's, IG Group, National Express, GSK and AstraZeneca
Zejula demonstrated a “statistically significant” improvement in progression free survival – the length of time a patient lives with the disease but it doesn’t get worse
Sir David Jack's team were responsible for the discovery of several huge drugs, and RPL554, a compound he helped develop later on in his career, is now being taken through the clinic by Verona
GSK wanted to show that Dovato was just as effective in suppressing HIV as the current cocktail of drugs given to HIV sufferers
Archive
Aside from the two housebuilders, corporate updates in the coming week will also be delivered by retailers Ocado, Superdry and Dunelm
GSK is in the middle of some big changes: it is bedding in a multi-billion-dollar acquisition; rebuilding its drugs pipeline; and merging its consumer healthcare division with one of its rivals
The Food & Drug Administration gave approval for GSK’s Nucala to be given using an auto-injector or a pre-filled safety syringe
Essentially, immuno-oncology involves developing drugs that use the body’s own immune system to fight cancers
Investments and investor services
The UK benchmark index closed over 56 points higher, at 7,353, aided by the fall in the pound
Archive
Numbers from Countryside Properties, National Grid, and Wincanton will also be among Thursday's highlights.
Archive
The week ahead's highlights include updates from Burberry, Land Securities, British Land, Premier Foods, Experian, Kingfisher, Aston Martin, Dignity, Centrica, Thomas Cook, On the Beach and Countryside Properties.
“Drug companies have to come clean about their prices in TV ads. If drug companies are ashamed of those prices – lower them!”
GSK has been ordered to pay US$89.7mln after its Ellipta inhalers were found to have breached Vectura’s patents
Revenue edged 6% higher in the quarter to £7.66bn, with almost all of that growth coming from the vaccines business
Archive
There’s a lot for investors to get their teeth into on Wednesday, with Sainsbury’s, GSK and Persimmon among the slew of companies reporting alongside Next
While the index does contain the heavyweights of the London market, they're not the most reliable indicator of how the UK's markets are actually performing