HealthPharma & Biotech
Amryt Pharma PLC

Amryt Pharma given permission to extend age eligibility for drug trial

Amryt is developing AP101 as a potential treatment for Epidermolysis Bullosa, where skin blisters to the touch

The condition is often present from birth

Amryt Pharma PLC (LON:AMYT) said it has been given permission to extend the age eligibility for its Phase III trial of a drug to treat a rare skin condition.

The study’s independent data monitoring committee has concluded that children aged between 21 days and four years can take part in the programme.

READ: Amryt Pharma adds new element to promising portfolio

Amryt is developing AP101 as a potential treatment for Epidermolysis Bullosa, where skin blisters to the touch.

The company’s chief executive, Joe Wiley, called the committee’s decision “a significant step forward”, adding it could help address an unmet need for a devastating condition, often present from birth.

“This development represents another milestone for Amryt as we build on our vision of becoming a global leader in rare and orphan diseases," he went on.

In a note to clients, analysts at ‘house’ broker Shore Capital said the update “demonstrates continued momentum at Amryt, following the significant positive interim efficacy update” at the start of January.

They added; “We continue to view Amryt as a compelling investment opportunity to gain exposure to a diversified rare disease platform, with a marketed drug for an ultra-rare disease, a further de-risked Phase III asset in an untapped $1bn market opportunity, and an attractive pre-clinical gene therapy platform.

“Our risk-adjusted sum-of-the-parts valuation suggests Lojuxta alone is worth c.20p/share, with the Phase III EB asset and early-stage pipeline not reflected.”

In early afternoon trading, Amryt Pharma shares were 0.3% higher at 15.55p.

 -- Adds analyst comment, share price --

Quick facts: Amryt Pharma PLC

Price: £1.23

Market: AIM
Market Cap: £61.97 m

Add related topics to MyProactive

Create your account: sign up and get ahead on news and events


The Company is a publisher. You understand and agree that no content published on the Site constitutes a recommendation that any particular security, portfolio of securities, transaction, or investment strategy is...

In exchange for publishing services rendered by the Company on behalf of Amryt Pharma PLC named herein, including the promotion by the Company of Amryt Pharma PLC in any Content on the Site, the Company receives from...



Amryt Pharma's Lojuxta approved for funding as NHS treatment

David Allmond, chief commercial officer at Amryt Pharma PLC (LON:AMYT) tells Proactive Investors their Lojuxta Homozygous Familial Hypercholesterolaemia (HoFH) treatment is to be made available to NHS patients in England. HoFH is a rare life-threatening disorder that causes abnormally...

on 10/7/18


Circular to Shareholders

2 days, 8 hours ago

Schedule One

1 week, 4 days ago

Schedule One - Amryt Pharma plc

1 week, 4 days ago

Holdings in Company

1 week, 6 days ago

Holding(s) in Company

2 weeks, 2 days ago

2 min read