Sign up Australia
Proactive Investors - Run By Investors For Investors

Anavex Life Sciences gets go-ahead from Spain to begin trial for its Parkinson's disease treatment

Its Phase 2 trial of Anavex 2-73 kicks off in Spain in the coming months
Elderly patient
The study's primary goal is to measure the cognition of patients with Parkinson's disease dementia

Anavex Life Sciences (NASDAQ:AVXL) today revealed that it has gotten the green light from the Spanish Agency for Medicinal Products and Medical Devices to introduce its Phase 2 trial of Anavex 2-73 for the treatment of Parkinson’s disease dementia.

The Phase 2 trial will be a double-blind, placebo-controlled 14-week study that will analyze 120 patients who will take either one of two different doses of Anavex2-73 or a placebo.

The primary goal of the study is to measure cognition and the secondary goals are to measure Parkinsonian motor symptoms and sleep function.

READ: Anavex Life's Alzheimer's drug awarded orphan status for child seizures

“We are excited about the approval to initiate the Phase 2 study of Anavex 2-73 for the treatment of Parkinson’s disease dementia, which will focus on the effect of Anavex 2-73 on both the cognitive and motor impairment of Parkinson’s disease,” said Christopher Missling, Anavex’s chief executive.

The trial, which kicks off in the coming months, will be held in Europe to start, but may expand to the US and Australia.

Parkinson’s is a neurological disorder, which can trigger dementia in its later stages.

Maxim cites cash on hand

The New York-based biopharma has sufficient cash on hand to fund its clinical trials, according to analyst Jason McCarthy of Maxim Group.

This month, Anavex entered into a so-called "at the market" sales agreement of its common stock for up to US$50mln.

“This, along with its current US$28mln in cash on the balance sheet, should be sufficient runway through the next series of catalysts including the completion of phase 2 studies in Parkinson’s disease with dementia, and Rett syndrome (both to initiate in 2H18) and potentially the P2b/3 in Alzheimer’s disease (AD, initiating 2H18),” wrote McCarthy in a note to investors.

He has a Buy rating and US$7 price target on the shares.

Anavex shares were 2% lower at US$3.37 in afternoon trade.

View full AVXL profile View Profile

Anavex Life Sciences Timeline

Related Articles

Vial of pills
June 25 2018
Cosmos is a modern company, but the trade routes it relies on are ancient
scientist in lab
August 31 2018
While the data bodes well for MTD201, Midatech is most excited by the validation of its Q-Sphera sustained release technology, which it is using in some of its other compounds
woman at a microscope
August 02 2018
Currently undergoing phase III clinical trials, AP101 is being developed to treat Epidermolysis Bullosa, a condition which occurs prominently in children and makes skin fragile to even the faintest touch

© Proactive Investors 2018

Proactive Investors Australia PTY LTD ACN:132787654 ABN:19132787654.

Market Indices, Commodities and Regulatory News Headlines copyright © Morningstar. Data delayed 15 minutes unless otherwise indicated. Terms of use