Synairgen PLC

Receive alerts
Market Cap:
£333.86 m
167.00 GBX
52 weeks high
52 weeks low

Synairgen has specialised scientific research and clinical teams dedicated to drug discovery and development in asthma, COPD and other respiratory diseases.

Their main activities are summarised opposite:


  • Advanced human in vitro models generated from the BioBank samples, including use of virus infection models (experienced in use of rhinovirus, RSV, influenza etc.)
  • Lung biomarker validation and assessment
  • Application of human tissue models for:
  • Target discovery
  • Target validity
  • Support clinical activity


  • Extensive BioBank of relevant tissue, cells, blood and airway secretions from volunteers (both diseased and healthy)
  • Phase I &II trial capability in respiratory patients during naturally acquired cold infections



Simon Shaw
Non-Executive Chairman

Simon Shaw joined Synairgen as executive Chairman on its inception in June 2003 and became non-executive Chairman in October of that year. He is Group Chief Financial Officer of Savills plc.

He was Chief Financial Officer of Gyrus Group PLC from 2003 until its sale to Olympus Corporation in 2008, having previously been Chief Operating Officer of Profile Therapeutics plc between 1998 and 2003. Between 1991 and 1997 he was a corporate financier, latterly at Hambros Bank Limited. He is a chartered accountant.

Richard Marsden
Chief Executive Officer

Richard Marsden joined Synairgen in a consulting role as General Manager in November 2003, was appointed to the Board as Managing Director in June 2004 and appointed Chief Executive Officer in September 2009. Between 1998 and 2003 he worked as Projects Manager and Cystic Fibrosis Business Development Manager at Profile Therapeutics plc, where he managed the Cystic Fibrosis business and played a major role in the development of its proprietary pharmaceutical unit, Profile Pharma Limited. Prior to this, he worked for Zimmer Limited, Genentech (UK) Limited and Roche Products Limited.

Dr Philip Monk
Chief Scientific Officer

Dr Phillip Monk joined Synairgen in October 2006 as Head of Bioscience Development and was appointed to the Board as Chief Scientific Officer in September 2009. Phillip was previously Director of the Respiratory and Inflammation Biology group at Cambridge Antibody Technology (‘CAT’) and led the scientific development of tralokinumab, an anti-IL-13 antibody being developed for the treatment of severe asthma.

Prior to joining CAT, he worked at Bayer AG within the respiratory disease therapeutic area, focusing on the development of novel therapies for asthma, COPD and cystic fibrosis.

John Ward
Finance Director

John Ward joined Synairgen in October 2004 as Finance Director. From December 1999 to July 2004 he was Chief Financial Officer and Company Secretary of Profile Therapeutics plc and was appointed to the Profile Therapeutics board in March 2003.

From 1996 to 1999 he was Finance Director of Rapid Deployment Group Limited, the UK holding company for the healthcare operations of Ventiv Health, Inc. Prior to joining Rapid Deployment he was a Director of Corporate Finance at Price Waterhouse. He is a chartered accountant.

Iain Buchanan
Non-Executive Director

Iain Buchanan was appointed as a non-executive director in June 2010 and brings to the company over 40 years of management experience in the pharmaceutical and biotech industries. Most recently he was CEO of NOXXON Pharma AG based in Berlin and previously he was CEO of Novexel S.A. based in Paris. He joined Novexel from Vertex Pharmaceuticals where he established the European affiliate. Prior to Vertex, Iain managed the international licensee business of Cilag AG – a subsidiary of Johnson and Johnson – based in Switzerland. Iain serves as Chairman of the Board for Adapsyn Bioscience Inc. and as a non-executive director for Allecra Therapeutics GmbH.

Dr Bruce Campbell
Non-Executive Director

Dr Bruce Campbell joined Synairgen as a non-executive Director in April 2006. He has 40 years of drug development experience and has developed many drugs in a wide range of indications which are now on the market. He currently acts as a consultant to various companies including Proximagen Limited. Formerly he was Senior VP of International Development at Neurocrine Biosciences, Inc. (‘Neurocrine’). Prior to joining Neurocrine he worked for 27 years at Servier (United Kingdom), latterly as Scientific Director. In addition, he has also been a director and European Chairman of the Drug Information Association, a member of the European ICH Safety Working Party and a scientific advisor to IP Group plc. He is a visiting Professor in Pharmacology at King’s College, London.

Prof. Stephen Holgate CBE
Non-Executive Director

Stephen Holgate is a co-founder of Synairgen and was appointed a non-executive director in June 2003. After qualifying in Medicine at Charing Cross Hospital Medical School, London he has pursued an academic career leading to his appointment in 1987 to his current position as Medical Research Council Clinical Professor of Immunopharmacology at the University of Southampton. His research interests have been largely focused on the cellular and molecular mechanisms of asthma that has involved use of both epidemiological and genetic approaches. He has published over 1000 papers in peer-reviewed literature.

He is currently: Chairman of the MRC Translational Research Group, Member of the MRC Strategy Board; Member of the Science Europe Medical Science Committee and Horizon 2020 Health Science Panel; Chairman of the European Respiratory Society Scientific Council; Board Chair of the National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs); Chairman of Defra’s Hazardous Substances Advisory Committee; Trustee of Cancer Research UK, the British Lung Foundation and The Kennedy Trust for Rheumatology Research; and a scientific board member or advisor to a number of companies, including Amgen, Takeda, Merck, and Novartis. In 2010, he was appointed by the Higher Education Funding Council for England to be the Chair of the Research Excellence Framework (REF2014) Main Panel A covering Medicine, Health and Life Sciences.


Head office
Synairgen plc /
Synairgen Research Ltd
Mailpoint 810
Southampton General Hospital
Tremona Road
SO16 6YD

Tel:  +44 (0) 23 8051 2800
Fax: +44 (0)23 8051 2800

Company details

Synairgen plc
Registered number: 5233429
Place of registration: England

Synairgen Research Ltd
Registered number: 4793696
Place of registration: England

The registered office address for both companies is:

Mailpoint 810
Southampton General Hospital
Tremona Road
SO16 6YD

Nominated adviser and broker

60 New Broad Street
Tel: +44 (0) 20 7220 0500


Arcadia House
Maritime Walk
Ocean Village
SO14 3TL
Tel: +44(0) 23 8088 1700


Link Market Services Limited
Northern House
Woodsome Park
Fenay Bridge

By phone – UK – Tel: 0371 664 0300 , from overseas call +44 (0) 371 664 0300. Calls cost 12p per minute plus your phone company’s access charge. Calls from outside the United Kingdom will be charged at the applicable international rate. We are open 9.00am to 5.30pm Monday – Friday, excluding public holidays in England and Wales.

By email – enquiries@linkgroup.co.uk


Fladgate LLP
16 Great Queen Street
Tel: +44 (0) 20 3036 7000

Financial PR

Consilium Strategic Communications
41 Lothbury
Tel: +44 (0) 20 3709 5701