Sign up Australia
Proactive Investors - Run By Investors For Investors

Novogen shares soar on the potential of its experimental anti ovarian cancer drug

Novogen shares soar on the potential of its experimental anti ovarian cancer drug

Novogen's (ASX:NRT) share price more than doubled after a study showed that its experimental anti-ovarian cancer drug CS-6 was highly active against ovarian cancer stem cells.

Share were up almost 311%, reaching a high of $0.37 a share.

While the drug has shown potent anti cancer activity against cancer cells, the study was designed to find whether the drug would also be effective against cancer stem cells.

Cancer stem cells have been identified in a range of cancers including ovarian, brain cancers and leukaemia and are almost completely resistant to radiotherapy and standard anti-cancer drugs.

With CS-6 showing dual activity, it would mark the drug as having significant potential as a comprehensive chemotherapy, targeting both the minority cancer stem cell as well as the majority non stem cells.

The study was done by Mazor Oncology, a spin off company of Yale Universtiy that has expertise in cancer stem cells.

Studies performed in the laboratory of Dr. Gil Mor at Yale University have identified and characterized ovarian cancer stem cells as the source of ovarian cancer recurrence.

Targeting these cells, therefore, represent a critical approach to prevent recurrence, the main cause of mortality in patients with ovarian cancer.

In laboratory tests conducted since Novogen acquired its new Triaxial drug technology, CS-6 has proved highly effective at stopping the growth of these cancer stem cells, eventually causing them to die.

The initial studies at Mazor Oncology show a highly effective cytotoxic effect on ovarian cancer stem cells, at low concentrations and within a short period of time.

The CS-6 belongs to a new class of drug candidates known as super benzopyrans displaying potent anti cancer activity.

Proactive Investors Australia is the market leader in producing news, articles and research reports on ASX “Small and Mid-cap” stocks with distribution in Australia, UK, North America and Hong Kong / China.

Register here to be notified of future NRT Company articles
View full NRT profile

Novogen Limited Timeline

August 05 2015

Related Articles

A graphic of a tumour growing in the body
July 07 2016
Nanobiotix is a late clinical-stage nanomedicine company researching novel approaches to enhance radiotherapy for the local treatment of cancer.
July 13 2016
Updating investors, the company said turnover will be around £48.5mln, representing a rise of 12%, or 19% once the figure is adjusted for currency movements.
Dendritic cells with T-lymphocytes
July 21 2016
With cases of skin cancer on the rise, Scancell's immunotherapy study data has come at the right time, but is it enough to offset the insecurity in the sector?

© Proactive Investors 2016

Proactive Investors Australia PTY LTD ACN:132787654 ABN:19132787654.